Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 18/20 | 0.59 |
| ▸ | CTSK | P43235 | 2/20 | 0.50 |
| ▸ | CTSS | P25774 | 1/20 | 0.50 |
| ▸ | FAP | Q12884 | 5/20 | 0.47 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.44 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5201959 | 1.00 | DPP4 (0.59) | DPP4CTSKCTSSFAPDPP7 | |
| SCHEMBL5201667 | 0.89 | DPP4 (0.50) | DPP4CTSKCTSSFAPDPP7 | |
| SCHEMBL5202268 | 0.86 | DPP4 (0.48) | DPP4FAPDPP7DPP8DPP9 | |
| SCHEMBL3612579 | 0.83 | CTSK (0.54) | DPP4CTSKCTSSDPP8DPP9 | |
| SCHEMBL5203122 | 0.82 | PIN1 (0.53) | DPP4CTSKCTSS | |
| SCHEMBL5205944 | 0.82 | PIN1 (0.53) | DPP4CTSKCTSS | |
| SCHEMBL5202254 | 0.81 | DPP4 (0.51) | DPP4FAPDPP7DPP8DPP9 | |
| SCHEMBL5206279 | 0.81 | DPP4 (0.59) | DPP4CTSKCTSSCTSLCTSB | |
| SCHEMBL5696186 | 0.81 | DPP4 (0.58) | DPP4CTSKCTSSDPP8DPP9 | |
| SCHEMBL9003137 | 0.81 | DPP4 (0.58) | DPP4CTSKCTSSDPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070112059-A1 | CYANOPYRROLIDINE DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD. | 2007-05-17 | — | — | US | disclosed |
| US-20070112205-A1 | CYANOPYRROLIDINE DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD. | 2007-05-17 | — | — | US | disclosed |
| EP-1746086-A1 | Cyanopyrrolidine derivatives | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2007-01-24 | — | — | EP | disclosed |
| US-20040072892-A1 | Cyanopyrrolidine derivatives | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2004-04-15 | — | — | US | disclosed |
| EP-1333025-A1 | CYANOPYRROLIDINE DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2003-08-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040072892-A1 | Cyanopyrrolidine derivatives | CCR9, OPRD1, CBR1 | DPP4 2412/4885CTSK 3996/4885CTSS 3839/4885 |
| US-20070112059-A1 | CYANOPYRROLIDINE DERIVATIVES | DPP4, DPP9, DPP3 | DPP4 1/4885CTSK 512/4885CTSS 467/4885 |
| US-20070112205-A1 | CYANOPYRROLIDINE DERIVATIVES | CBR3, CBR1, TERT | DPP4 3721/4885CTSK 3512/4885CTSS 2883/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.