Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8314411 | 0.90 | ALDH1A1 (0.38) | ALDH1A1KDM4EEPHX2KMT2AMEN1 | |
| SCHEMBL8317748 | 0.85 | ALDH1A1 (0.36) | ALDH1A1KDM4EKMT2AMEN1POLB | |
| SCHEMBL8315607 | 0.85 | EPHX2 (0.39) | ALDH1A1KDM4EEPHX2KMT2AMEN1 | |
| SCHEMBL24359573 | 0.82 | EPHX2 (0.56) | ALDH1A1KDM4EEPHX2KMT2AMEN1 | |
| SCHEMBL31083654 | 0.75 | CYP11B1 (0.53) | ALDH1A1KMT2AMEN1OPRM1OPRL1 | |
| SCHEMBL13150727 | 0.75 | CYP11B1 (0.53) | ALDH1A1KMT2AMEN1OPRM1OPRL1 | |
| SCHEMBL6540849 | 0.70 | KMT2A (0.50) | EPHX2KMT2AMEN1TP53DRD3 | |
| SCHEMBL9375313 | 0.70 | ALDH1A1 (0.47) | ALDH1A1KDM4EKMT2AMEN1OPRM1 | |
| SCHEMBL8315186 | 0.70 | APOBEC3G (0.42) | ALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL22278578 | 0.69 | KMT2A (0.46) | ALDH1A1KDM4EEPHX2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536419-B1 | TRICYCLIC TRIAZOLE DERIVATIVES, PRODUCTION AND USE THEREOF | TORAY INDUSTRIES (JP) | 1999-10-13 | — | — | EP | disclosed |
| US-5683998-A | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS, ANTIPAF AGENTS | TORAY INDUSTRIES, INC. (JP) | 1997-11-04 | — | — | US | disclosed |