Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CMA1 | P23946 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8315186 | 0.85 | APOBEC3G (0.42) | MAPTKDM4EALDH1A1HTR2CAPOBEC3G | |
| SCHEMBL8316573 | 0.85 | ALDH1A1 (0.38) | EPHX2KDM4EALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL24359573 | 0.82 | EPHX2 (0.56) | EPHX2MAPTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL30964312 | 0.80 | MAOB (0.56) | MAPTHTR2CKMT2AMEN1PGR | |
| SCHEMBL8314411 | 0.78 | ALDH1A1 (0.38) | EPHX2MAPTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL13150265 | 0.75 | CYP11B1 (0.53) | EPHX2MAPTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL6540315 | 0.74 | PGR (0.49) | PGR | |
| SCHEMBL7173876 | 0.73 | KDM4E (0.42) | EPHX2MAPTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL6540849 | 0.70 | KMT2A (0.50) | EPHX2MAPTAHRKMT2AMAPK1 | |
| SCHEMBL8317748 | 0.70 | ALDH1A1 (0.36) | KDM4EALDH1A1APOBEC3GKMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536419-B1 | TRICYCLIC TRIAZOLE DERIVATIVES, PRODUCTION AND USE THEREOF | TORAY INDUSTRIES (JP) | 1999-10-13 | — | — | EP | disclosed |
| US-5683998-A | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS, ANTIPAF AGENTS | TORAY INDUSTRIES, INC. (JP) | 1997-11-04 | — | — | US | disclosed |
| EP-0536419-A1 | TRICYCLIC TRIAZOLE DERIVATIVE, PRODUCTION THEREOF, AND USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 1993-04-14 | — | — | EP | disclosed |