Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 1/20 | 0.48 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.48 |
| ▸ | CDK1 | P06493 | 1/20 | 0.48 |
| ▸ | CDK4 | P11802 | 1/20 | 0.48 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.48 |
| ▸ | CCND1 | P24385 | 1/20 | 0.48 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.48 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | FBP1 | P09467 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6703333 | 0.82 | KMT2A (0.53) | NPC1RAB9AHPGDMAPTALDH1A1 | |
| SCHEMBL4398615 | 0.79 | ALDH1A1 (0.54) | CCNB2CCNE2CDK1CDK4CCNB1 | |
| SCHEMBL19403467 | 0.77 | ALDH1A1 (0.52) | NPC1RAB9AHPGDMAPTALDH1A1 | |
| SCHEMBL1121674 | 0.76 | NPC1 (0.53) | NPC1RAB9AHPGDMAPTALDH1A1 | |
| SCHEMBL11736051 | 0.75 | L3MBTL1 (0.54) | NPC1RAB9AHPGDMAPTALDH1A1 | |
| SCHEMBL29740011 | 0.74 | PPARA (0.55) | PPARGCTSSCTSK | |
| SCHEMBL28656119 | 0.74 | PPARA (0.55) | PPARGCTSSCTSK | |
| SCHEMBL2213224 | 0.74 | HPGD (0.56) | NPC1RAB9AHPGDMAPTALDH1A1 | |
| SCHEMBL7867128 | 0.73 | FFAR1 (0.55) | CCNB2CCNE2CDK1CDK4CCNB1 | |
| SCHEMBL8639480 | 0.73 | NPC1 (0.50) | NPC1RAB9AHPGDMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048368-A2 | HETEROARYLSULFONYLMETHYL HYDROXAMIC ACIDS AND AMIDES AND THEIR USE AS PROTEASE INHIBITORS | PHARMACIA CORPORATION (US) | 2004-06-10 | — | — | WO | disclosed |