Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13299611 | 0.80 | KMT2A (0.53) | RAB9ANPC1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL13299630 | 0.79 | MAPT (0.44) | RAB9ANPC1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL6206228 | 0.75 | TSHR (0.51) | RAB9ANPC1MMP1MMP9MMP13 | |
| SCHEMBL8312489 | 0.75 | CA2 (0.34) | RAB9AALDH1A1KMT2AHSD17B10PKM | |
| SCHEMBL1478276 | 0.74 | F2 (0.51) | RAB9ANPC1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL10916089 | 0.71 | NPC1 (0.49) | RAB9ANPC1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL878312 | 0.70 | CYP2D6 (0.53) | RAB9ANPC1ALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL28399625 | 0.70 | RECQL (0.51) | RAB9ANPC1ALDH1A1TSHR | |
| SCHEMBL13299619 | 0.70 | PKM (0.48) | RAB9ANPC1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL5464840 | 0.69 | F2 (0.50) | RAB9ANPC1ALDH1A1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048368-A2 | HETEROARYLSULFONYLMETHYL HYDROXAMIC ACIDS AND AMIDES AND THEIR USE AS PROTEASE INHIBITORS | PHARMACIA CORPORATION (US) | 2004-06-10 | — | — | WO | disclosed |