Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.34 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.32 |
| ▸ | PHGDH | O43175 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | PTPRC | P08575 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.30 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.30 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.30 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.30 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8316809 | 0.75 | RAB9A (0.42) | KMT2AALDH1A1TP53MAPTPKM | |
| SCHEMBL8313400 | 0.72 | MMP13 (0.34) | CA2CA12CA1LMNACCNB2 | |
| SCHEMBL8313376 | 0.72 | MMP13 (0.46) | — | |
| SCHEMBL8321172 | 0.69 | KMT2A (0.38) | CA2PHGDHKMT2ACA12CA1 | |
| SCHEMBL6932753 | 0.68 | KMT2A (0.48) | CA2PHGDHKMT2ACA1HSD11B1 | |
| SCHEMBL5908693 | 0.68 | PLCG1 (0.47) | CA2PHGDHKMT2ACA1LMNA | |
| SCHEMBL6932007 | 0.67 | HTT (0.53) | KMT2ANPSR1HSD11B1ALDH1A1MAPT | |
| SCHEMBL5908893 | 0.65 | CA12 (0.44) | CA2PHGDHKMT2ACA12CA1 | |
| SCHEMBL3450703 | 0.64 | HSD11B1 (0.42) | PHGDHKMT2AHSD11B1ALDH1A1RAB9A | |
| SCHEMBL34466603 | 0.64 | HSD11B1 (0.42) | PHGDHKMT2AHSD11B1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048368-A2 | HETEROARYLSULFONYLMETHYL HYDROXAMIC ACIDS AND AMIDES AND THEIR USE AS PROTEASE INHIBITORS | PHARMACIA CORPORATION (US) | 2004-06-10 | — | — | WO | disclosed |