Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8317056 | 1.00 | TUBB1 (0.33) | TUBB1NPC1RAB9ALMNAPOLB | |
| Hydrochloric Acid SCHEMBL8317457 | 0.89 | TUBB4A (0.36) | TUBB1 | |
| Hydrochloric Acid SCHEMBL8317455 | 0.89 | TUBB4A (0.36) | TUBB1 | |
| SCHEMBL8313688 | 0.88 | TUBB1 (0.36) | TUBB1NPC1RAB9APOLBMAPT | |
| SCHEMBL8313691 | 0.88 | TUBB1 (0.36) | TUBB1NPC1RAB9APOLBMAPT | |
| SCHEMBL8316004 | 0.86 | FGF23 (0.36) | NPC1RAB9ALMNAPOLBMAPT | |
| SCHEMBL8316008 | 0.86 | FGF23 (0.36) | NPC1RAB9ALMNAPOLBMAPT | |
| SCHEMBL8315608 | 0.83 | CHAT (0.36) | NPC1RAB9AMAPT | |
| SCHEMBL8315610 | 0.83 | CHAT (0.36) | NPC1RAB9AMAPT | |
| SCHEMBL9694219 | 0.82 | ALDH1A1 (0.45) | TUBB1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0351856-B1 | Thiazolo[5,4-b]azepine compounds | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-09-15 | — | — | EP | disclosed |
| US-5300639-A | 2-oxo-3-carbonylamino-substituted azepine intermediates; lipoperoxide formation inhibitors | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-04-05 | — | — | US | disclosed |
| US-5118806-A | Enzyme inhibitor for lipoxygenase; useful for treating cancer, hepatic diseases, inflammation, cerebrovascular diseases | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-06-02 | — | — | US | disclosed |
| US-4956360-A | LIPOPEROXIDE INHIBITORS, ENZYME INHIBITORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-09-11 | — | — | US | disclosed |