Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
| ▸ | NPY2R | P49146 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8315774 | 0.87 | AKR1B1 (0.35) | AKR1B1ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL8313797 | 0.79 | ALDH1A1 (0.35) | ALDH1A1MEN1KMT2APOLBTDP1 | |
| SCHEMBL8308734 | 0.79 | AKR1B1 (0.43) | AKR1B1ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL6270429 | 0.75 | AKR1B1 (0.40) | AKR1B1ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL8313587 | 0.74 | L3MBTL1 (0.41) | AKR1B1ALDH1A1KMT2AMALT1LMNA | |
| SCHEMBL8312851 | 0.74 | TLR3 (0.38) | AKR1B1ALDH1A1MEN1KMT2AMALT1 | |
| SCHEMBL8311414 | 0.74 | AKR1B1 (0.39) | AKR1B1ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL8315687 | 0.74 | AKR1B1 (0.41) | AKR1B1ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL8315630 | 0.73 | KDM4E (0.48) | ALDH1A1MEN1KMT2ATDP1CA9 | |
| SCHEMBL8796257 | 0.72 | ALDH1A1 (0.36) | AKR1B1ALDH1A1MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0632033-B1 | NOVEL BENZOPYRAN DERIVATIVE | CHUGAI PHARMACEUTICAL CO LTD (JP) | 1999-04-07 | — | — | EP | disclosed |
| US-5646308-A | POTASSIUM CHANNEL ACTIVATORS USED AS ANTIASTHMATICS, ANTIEPILEPTICS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1997-07-08 | — | — | US | disclosed |
| EP-0632033-A1 | NOVEL BENZOPYRAN DERIVATIVE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1995-01-04 | — | — | EP | disclosed |