Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK2D | Q13557 | 3/20 | 0.48 |
| ▸ | PRKCB | P05771 | 2/20 | 0.41 |
| ▸ | PRKCA | P17252 | 2/20 | 0.41 |
| ▸ | PRKCH | P24723 | 1/20 | 0.41 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.41 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.41 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CCR6 | P51684 | 1/20 | 0.37 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 2/20 | 0.34 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ATP4A | P20648 | 2/20 | 0.34 |
| ▸ | ATP4B | P51164 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8316483 | 0.85 | CAMK2D (0.51) | CAMK2DPRKCBPRKCAPRKCHPRKCE | |
| SCHEMBL8578932 | 0.84 | CAMK2D (0.44) | CAMK2DPRKCBPRKCAPRKCHPRKCE | |
| SCHEMBL8317078 | 0.83 | CAMK2D (0.48) | CAMK2DPRKCBPRKCAPRKCHPRKCE | |
| Hydrochloric Acid SCHEMBL8318720 | 0.82 | CAMK2D (0.48) | CAMK2DPRKCBPRKCAPRKCHPRKCE | |
| SCHEMBL8318435 | 0.80 | CAMK2D (0.48) | CAMK2DPRKCBPRKCAPRKCHPRKCE | |
| Hydrochloric Acid SCHEMBL8319148 | 0.79 | CAMK2D (0.47) | CAMK2DPRKCBPRKCAPRKCHPRKCE | |
| SCHEMBL8317050 | 0.79 | CAMK2D (0.45) | CAMK2DPRKCBPRKCAPRKCHPRKCE | |
| SCHEMBL7785201 | 0.78 | CAMK2D (0.61) | CAMK2DPRKCBPRKCAPRKCHPRKCE | |
| SCHEMBL5686050 | 0.78 | CAMK2D (0.57) | CAMK2DPRKCBPRKCAPRKCHPRKCE | |
| Hydrochloric Acid SCHEMBL8319189 | 0.77 | PRKCB (0.49) | CAMK2DPRKCBPRKCAPRKCHPRKCE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0925296-A1 | NEW PHARMACEUTICALLY ACTIVE COMPOUNDS | Astra Aktiebolag (SE) | 1999-06-30 | — | — | EP | claimed |
| WO-1998011102-A1 | NEW PHARMACEUTICALLY ACTIVE COMPOUNDS | ASTRA AKTIEBOLAG (SE) | 1998-03-19 | — | — | WO | claimed |
| EP-0925296-A1 | NEW PHARMACEUTICALLY ACTIVE COMPOUNDS | Astra Aktiebolag (SE) | 1999-06-30 | — | — | EP | disclosed |
| WO-1998011102-A1 | NEW PHARMACEUTICALLY ACTIVE COMPOUNDS | ASTRA AKTIEBOLAG (SE) | 1998-03-19 | — | — | WO | disclosed |