Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 9/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.59 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.59 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.59 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.59 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.59 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.59 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.52 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8314600 | 0.89 | PKM (0.58) | TDP1HDAC1HDAC8HDAC6HDAC3 | |
| SCHEMBL8318925 | 0.81 | HDAC1 (0.53) | HDAC1HDAC8HDAC6HDAC3HDAC4 | |
| SCHEMBL3458189 | 0.81 | HDAC1 (0.65) | TDP1HDAC1HDAC8HDAC6HDAC3 | |
| SCHEMBL3458190 | 0.81 | HDAC1 (0.65) | TDP1HDAC1HDAC8HDAC6HDAC3 | |
| SCHEMBL8320461 | 0.78 | EGFR (0.52) | HDAC1HDAC8HDAC6HDAC3HDAC4 | |
| SCHEMBL6673273 | 0.77 | TDP1 (0.76) | TDP1HDAC1HDAC8HDAC6HDAC3 | |
| SCHEMBL6673267 | 0.77 | TDP1 (0.76) | TDP1HDAC1HDAC8HDAC6HDAC3 | |
| SCHEMBL6673269 | 0.77 | TDP1 (0.76) | TDP1HDAC1HDAC8HDAC6HDAC3 | |
| SCHEMBL3380973 | 0.77 | TDP1 (1.00) | TDP1HDAC1HDAC8HDAC6HDAC3 | |
| SCHEMBL3380977 | 0.77 | TDP1 (1.00) | TDP1HDAC1HDAC8HDAC6HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004071401-A2 | HYDROXAMIC ACID DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS (HDCA) | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-26 | — | — | WO | disclosed |