Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 9/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 8/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 8/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 6/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 6/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 6/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.53 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.49 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.49 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8320461 | 0.84 | EGFR (0.52) | HDAC1HDAC3HDAC4HDAC2HDAC8 | |
| SCHEMBL8317390 | 0.81 | TDP1 (0.61) | HDAC1HDAC3HDAC4HDAC2HDAC8 | |
| SCHEMBL30530178 | 0.79 | SLC6A9 (0.71) | SLC6A9SLC6A5UTS2R | |
| SCHEMBL28466273 | 0.78 | SLC6A9 (0.68) | SLC6A9SLC6A5UTS2R | |
| SCHEMBL8317458 | 0.76 | PKM (0.49) | HDAC1HDAC3HDAC4HDAC2HDAC8 | |
| SCHEMBL3458189 | 0.76 | HDAC1 (0.65) | HDAC1HDAC3HDAC4HDAC2HDAC8 | |
| SCHEMBL3458190 | 0.76 | HDAC1 (0.65) | HDAC1HDAC3HDAC4HDAC2HDAC8 | |
| SCHEMBL28466269 | 0.75 | HPGDS (0.72) | SLC6A9SLC6A5 | |
| SCHEMBL26961108 | 0.73 | HDAC1 (0.68) | HDAC1HDAC3HDAC4HDAC2HDAC8 | |
| SCHEMBL8320373 | 0.72 | HDAC1 (0.57) | HDAC1HDAC3HDAC4HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004071401-A2 | HYDROXAMIC ACID DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS (HDCA) | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-26 | — | — | WO | disclosed |