Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | KIF11 | P52732 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.45 |
| ▸ | CACNA1C | Q13936 | 3/20 | 0.45 |
| ▸ | KCNK2 | O95069 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.45 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.44 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.44 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.44 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL605443 | 0.80 | HTR2A (0.64) | ACP3TSHRALDH1A1KIF11SLC6A3 | |
| SCHEMBL7074111 | 0.80 | ACP3 (0.51) | ACP3TSHRALDH1A1KIF11SLC6A3 | |
| SCHEMBL12086021 | 0.80 | ACP3 (0.51) | ACP3TSHRALDH1A1KIF11SLC6A3 | |
| SCHEMBL1666064 | 0.80 | HTR2A (0.52) | TSHRALDH1A1MTORRAB9AHTR2A | |
| SCHEMBL7523008 | 0.79 | ACP3 (0.55) | ACP3TSHRALDH1A1KIF11SLC6A3 | |
| SCHEMBL7783843 | 0.78 | HSD11B1 (0.50) | ACP3KIF11HSD11B1PDPK1CNR2 | |
| SCHEMBL5161949 | 0.77 | HRH1 (0.67) | ACP3TSHRALDH1A1SLC6A3SLC6A4 | |
| SCHEMBL8233890 | 0.77 | ACP3 (0.47) | ACP3TSHRALDH1A1KIF11CACNA1C | |
| SCHEMBL28495393 | 0.77 | TSHR (0.56) | ACP3TSHRALDH1A1KIF11SLC6A3 | |
| SCHEMBL6703510 | 0.76 | ACP3 (0.51) | ACP3TSHRALDH1A1KIF11SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0929534-A1 | TRYCYCLIC COMPOUNDS AS PROSTAGLANDIN I2 RECEPTOR AGONISTS | Takeda Pharmaceutical Company Limited (JP) | 1999-07-21 | — | — | EP | disclosed |
| WO-1998013356-A1 | TRYCYCLIC COMPOUNDS AS PROSTAGLANDIN I2 RECEPTOR AGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-04-02 | — | — | WO | disclosed |