Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.64 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.64 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.59 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.53 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.53 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | ACP3 | P15309 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | SLC7A5 | Q01650 | 4/20 | 0.49 |
| ▸ | KIF11 | P52732 | 1/20 | 0.48 |
| ▸ | PNMT | P11086 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.45 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.44 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5161949 | 0.85 | HRH1 (0.67) | HTR2ATAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4743517 | 0.85 | HTR2A (0.59) | HTR2ATAAR1CHRNB2CHRNA4CACNA1C | |
| SCHEMBL1581317 | 0.84 | PNMT (0.45) | HTR2ATAAR1CHRNB2CHRNA4SLC6A2 | |
| Hydrochloric Acid SCHEMBL4433367 | 0.83 | HRH1 (0.64) | HTR2ASLC6A2SLC6A4SLC6A3CACNA1C | |
| 2,2,2-Trifluoroethanaminium SCHEMBL4716808 | 0.81 | HTR2A (0.73) | HTR2ATAAR1CHRNB2CHRNA4SLC6A2 | |
| SCHEMBL12086021 | 0.80 | ACP3 (0.51) | HTR2ASLC6A2SLC6A4SLC6A3CACNA1C | |
| SCHEMBL7074111 | 0.80 | ACP3 (0.51) | HTR2ASLC6A2SLC6A4SLC6A3CACNA1C | |
| SCHEMBL8317456 | 0.80 | ACP3 (0.51) | HTR2ASLC6A2SLC6A4SLC6A3CACNA1C | |
| SCHEMBL149259 | 0.80 | HTR2A (1.00) | HTR2ATAAR1CHRNB2CHRNA4SLC6A2 | |
| SCHEMBL2010847 | 0.79 | ACP3 (0.55) | SLC6A2SLC6A4SLC6A3CACNA1CKCNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025051829-A1 | NEW PROP-2-YNAMIDE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-03-13 | — | — | WO | disclosed |
| EP-2299275-B1 | Classification of the oncofetal fibronection level for pregnancy-related indications | ADEZA BIOMEDICAL CORP (US) | 2018-03-07 | — | — | EP | disclosed |
| US-9513298-B2 | Methods for detecting oncofetal fibronectin | BANK OF AMERICA, N.A., AS COLLATERAL AGENT | 2016-12-06 | — | — | US | disclosed |
| US-20150044708-A1 | Methods for Detecting Oncofetal Fibronectin | HOLOGIC, INC. | 2015-02-12 | — | — | US | disclosed |
| US-8852872-B2 | Methods for detecting oncofetal fibronectin | HOLOGIC, INC. (US) | 2014-10-07 | — | — | US | disclosed |
| US-20130171672-A1 | Methods for Detecting Oncofetal Fibronectin | HOLOGIC, INC. (US) | 2013-07-04 | — | — | US | disclosed |
| US-8372581-B2 | Methods for detecting oncofetal fibronectin | CYTYC CORPORATION (US) | 2013-02-12 | — | — | US | disclosed |
| US-20120040356-A1 | Methods for Detecting Oncofetal Fibronectin | CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP | 2012-02-16 | — | — | US | disclosed |
| EP-1778874-B1 | ONCOFETAL FIBRONECTIN AS A MARKER FOR CERVICAL CANCER | ADEZA BIOMEDICAL CORP (US) | 2011-11-23 | — | — | EP | disclosed |
| EP-2299275-A2 | Classification of the oncofetal fibronection level for the indication of diseases and other conditions | ADEZA BIOMEDICAL CORPORATION (US) | 2011-03-23 | — | — | EP | disclosed |
| WO-2008106633-A1 | METHODS OF USING BENZODIOXINE COMPOUNDS IN TREATING SODIUM CHANNEL-MEDIATED DISEASES OR CONDITIONS | XENON PHARMACEUTICALS INC. (CA) | 2008-09-04 | — | — | WO | disclosed |
| EP-1778874-A2 | ONCOFETAL FIBRONECTIN AS A MARKER FOR DISEASE AND OTHER CONDITIONS AND METHODS FOR DETECTION OF ONCOFETAL FIBRONECTIN | ADEZA BIOMEDICAL CORPORATION (US) | 2007-05-02 | — | — | EP | disclosed |
| WO-2006026020-A9 | ONCOFETAL FIBRONECTIN AS A MARKER FOR DISEASE AND OTHER CONDITIONS AND METHODS FOR DETECTION OF ONCOFETAL FIBRONECTIN | ADEZA BIOMEDICAL CORP (US) | 2006-07-06 | — | — | WO | disclosed |
| WO-2006026020-A2 | ONCOFETAL FIBRONECTIN AS A MARKER FOR DISEASE AND OTHER CONDITIONS AND METHODS FOR DETECTION OF ONCOFETAL FIBRONECTIN | ADEZA BIOMEDICAL CORPORATION (US) | 2006-03-09 | — | — | WO | disclosed |
| US-20060024724-A1 | Oncofetal fibronectin as a marker for health and disease | CYTYC SURGICAL PRODUCTS II LIMITED PARTNERSHIP | 2006-02-02 | — | — | US | disclosed |
| US-20060024725-A1 | Oncofetal fibronectin as a marker for pregnancy-related indications | THIRD WAVE TECHNOLOGIES, INC. | 2006-02-02 | — | — | US | disclosed |
| US-20060024757-A1 | Detection of oncofetal fibronectin for selection of concepti | CYTYC SURGICAL PRODUCTS II LIMITED PARTNERSHIP | 2006-02-02 | — | — | US | disclosed |
| US-20060024722-A1 | Samples for detection of oncofetal fibronectin and uses thereof | BIOLUCENT, LLC | 2006-02-02 | — | — | US | disclosed |
| US-20060024723-A1 | Methods for detecting oncofetal fibronectin | CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP | 2006-02-02 | — | — | US | disclosed |