Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8315810 | 0.81 | CYP1A1 (0.45) | KDM4EALDH1A1HPGDMAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL8314842 | 0.79 | KDM4E (0.44) | PTGS2KDM4EALDH1A1HPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL8315136 | 0.77 | ACHE (0.36) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| Hydrochloric Acid SCHEMBL8315182 | 0.76 | PARP1 (0.37) | KDM4EALDH1A1HPGDHSD17B10TDP1 | |
| Hydrochloric Acid SCHEMBL8312117 | 0.73 | RAB9A (0.42) | ADORA1KDM4EALDH1A1HSD17B10TDP1 | |
| SCHEMBL10434591 | 0.72 | PDCD1 (0.34) | KDM4EALDH1A1HPGDLMNAMAPT | |
| Oxalic Acid SCHEMBL8313128 | 0.72 | CYP1A1 (0.40) | KDM4EALDH1A1LMNAMAPTMAPK1 | |
| Oxalic Acid SCHEMBL8313123 | 0.72 | CYP1A1 (0.40) | KDM4EALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL8316374 | 0.72 | MAPT (0.49) | ADORA1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8316269 | 0.72 | ACHE (0.39) | KDM4EALDH1A1MGAMGAASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0351856-B1 | Thiazolo[5,4-b]azepine compounds | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-09-15 | — | — | EP | disclosed |
| US-5118806-A | Enzyme inhibitor for lipoxygenase; useful for treating cancer, hepatic diseases, inflammation, cerebrovascular diseases | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-06-02 | — | — | US | disclosed |
| US-4956360-A | LIPOPEROXIDE INHIBITORS, ENZYME INHIBITORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-09-11 | — | — | US | disclosed |