Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 6/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 6/20 | 0.34 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8317403 | 0.84 | ACHE (0.39) | KDM4ENPC1ALDH1A1LMNAGLA | |
| SCHEMBL8316269 | 0.81 | ACHE (0.39) | KDM4EALDH1A1GAARAB9A | |
| Hydrochloric Acid SCHEMBL8313444 | 0.79 | ALDH1A1 (0.39) | KDM4ENPC1ALDH1A1MAPTHPGD | |
| Hydrochloric Acid SCHEMBL8313470 | 0.78 | ACHE (0.40) | PDCD1CD274NUDT1KDM4EALDH1A1 | |
| SCHEMBL8314378 | 0.77 | RAB9A (0.40) | KDM4ENPC1ALDH1A1LMNAMAPT | |
| Hydrochloric Acid SCHEMBL8315904 | 0.76 | ACHE (0.39) | NUDT1KDM4EALDH1A1LMNAHPGD | |
| Hydrochloric Acid SCHEMBL8311899 | 0.76 | RAB9A (0.39) | KDM4ENPC1ALDH1A1LMNAMAPT | |
| SCHEMBL8314532 | 0.74 | RAB9A (0.40) | NUDT1KDM4ENPC1ALDH1A1LMNA | |
| SCHEMBL8315862 | 0.74 | ALOX5 (0.44) | KDM4ENPC1ALDH1A1LMNAGAA | |
| Hydrochloric Acid SCHEMBL8315136 | 0.74 | ACHE (0.36) | KDM4EALDH1A1GLAGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4956360-A | LIPOPEROXIDE INHIBITORS, ENZYME INHIBITORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-09-11 | — | — | US | claimed |
| EP-0351856-A2 | Thiazolo[5,4-b]azepine compounds | Takeda Chemical Industries, Ltd. (JP) | 1990-01-24 | — | — | EP | claimed |