Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | PLK1 | P53350 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8314234 | 0.90 | ALDH1A1 (0.45) | GAAPLK1ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL8313733 | 0.83 | ALDH1A1 (0.44) | GAAPLK1ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL8317752 | 0.69 | ADORA2A (0.39) | GAAPLK1ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL19538752 | 0.68 | ALDH1A1 (0.37) | GAAPLK1ALDH1A1TDP1MAPT | |
| SCHEMBL29941758 | 0.68 | ALDH1A1 (0.64) | GAAPLK1ALDH1A1 | |
| SCHEMBL10090172 | 0.68 | ALDH1A1 (0.64) | GAAPLK1ALDH1A1 | |
| SCHEMBL13490798 | 0.68 | ALDH1A1 (0.51) | GAAPLK1ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL8311294 | 0.68 | APOBEC3G (0.42) | PLK1ALDH1A1POLBTSHRTP53 | |
| SCHEMBL19411168 | 0.66 | ALDH1A1 (0.49) | GAAPLK1ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL19411176 | 0.66 | ALDH1A1 (0.49) | GAAPLK1ALDH1A1SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536419-B1 | TRICYCLIC TRIAZOLE DERIVATIVES, PRODUCTION AND USE THEREOF | TORAY INDUSTRIES (JP) | 1999-10-13 | — | — | EP | disclosed |
| EP-0536419-A1 | TRICYCLIC TRIAZOLE DERIVATIVE, PRODUCTION THEREOF, AND USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 1993-04-14 | — | — | EP | disclosed |