Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.40 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GRK2 | P25098 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8316645 | 1.00 | EGLN2 (0.46) | EGLN2MMP2MAPTHTTSAE1 | |
| SCHEMBL3267016 | 1.00 | EGLN2 (0.46) | EGLN2MMP2MAPTHTTSAE1 | |
| SCHEMBL407716 | 0.80 | ALDH1A1 (0.45) | EGLN2MAPTHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL28956694 | 0.80 | ALDH1A1 (0.45) | EGLN2MAPTHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL7275456 | 0.80 | ABCC9 (0.44) | MMP2MAPTHTTSAE1UBA2 | |
| SCHEMBL1724786 | 0.76 | EGLN2 (0.44) | EGLN2GLAMEN1KMT2A | |
| SCHEMBL12126047 | 0.76 | MAPT (0.44) | MAPTHTTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL28827422 | 0.76 | MAPT (0.41) | MAPTHTTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL33651 | 0.76 | MAPT (0.41) | MAPTHTTSMN1; SMN2ALDH1A1ADRB2 | |
| SCHEMBL18412373 | 0.76 | LOXL2 (0.44) | MMP2SAE1UBA2ALDH1A1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623615-B1 | Substituted 1-phenyl-oxazolidin-2-one derivatives, their preparation and their use as adhesion-receptor antagonists | MERCK PATENT GMBH (DE) | 1999-06-30 | — | — | EP | disclosed |
| US-5532255-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-07-02 | — | — | US | disclosed |
| EP-0623615-A1 | Adhesion-receptor antagonists | MERCK PATENT GmbH (DE) | 1994-11-09 | — | — | EP | disclosed |