Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27082533 | 0.93 | KCNA3 (0.33) | KCNA3CHRM1 | |
| SCHEMBL27082291 | 0.77 | KCNA3 (0.42) | KCNA3CHRM1 | |
| SCHEMBL8319137 | 0.74 | TSHR (0.53) | TSHRHTTHSD17B10 | |
| SCHEMBL8106592 | 0.74 | ALDH1A1 (0.36) | CHRM1 | |
| SCHEMBL22996026 | 0.73 | KCNA3 (0.45) | KCNA3CHRM1 | |
| SCHEMBL17339732 | 0.71 | OPRM1 (0.40) | TSHRHTTHSD17B10 | |
| SCHEMBL2767 | 0.71 | SLC6A4 (0.53) | TSHRHTT | |
| SCHEMBL16291586 | 0.71 | SLC6A2 (0.54) | — | |
| SCHEMBL22978798 | 0.71 | KCNA3 (0.44) | KCNA3CHRM1 | |
| SCHEMBL11588203 | 0.71 | NPC1 (0.39) | CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923536-A1 | ARYLCYCLOALKANE CARBOXYLIC ESTERS, THEIR USE, PHARMACEUTICAL COMPOSITIONS AND PREPARATION | Pharmacia & Upjohn Aktiebolag (SE) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998004517-A1 | ARYLCYCLOALKANE CARBOXYLIC ESTERS, THEIR USE, PHARMACEUTICAL COMPOSITIONS AND PREPARATION | PHARMACIA & UPJOHN AB (SE) | 1998-02-05 | — | — | WO | disclosed |