Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.46 |
| ▸ | CFTR | P13569 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | LIPE | Q05469 | 1/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | GPR3 | P46089 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10985952 | 0.83 | BCHE (0.50) | BCHEACHEFFAR4CNR1TP53 | |
| SCHEMBL10988447 | 0.80 | BCHE (0.66) | BCHEACHEFFAR4TP53LIPE | |
| SCHEMBL20773327 | 0.77 | PTGES2 (0.47) | FFAR4TP53SMN1; SMN2GAAGPR3 | |
| SCHEMBL20773580 | 0.76 | CTDSP1 (0.46) | FFAR4CFTRTP53KMT2ASMN1; SMN2 | |
| SCHEMBL23084377 | 0.76 | GPR3 (0.41) | FFAR4TP53SMN1; SMN2GAAGPR3 | |
| SCHEMBL3653050 | 0.76 | GAA (0.52) | MAPTKMT2AMEN1GAATDP1 | |
| SCHEMBL17774540 | 0.73 | GAA (0.50) | MAPTKMT2AMEN1HTTGAA | |
| SCHEMBL28016377 | 0.73 | HTT (0.43) | BCHEACHEFFAR4CNR1TP53 | |
| SCHEMBL28952666 | 0.71 | ALDH1A1 (0.53) | BCHEACHEFFAR4TP53LIPE | |
| SCHEMBL10976631 | 0.71 | HSD11B1 (0.58) | BCHEACHEFFAR4CNR1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0966473-A1 | THIAZOLOBENZOHETEROCYCLES, PREPARATION AND MEDICINES CONTAINING SAME | Aventis Pharma S.A. (FR) | 1999-12-29 | — | — | EP | disclosed |
| WO-1998038194-A1 | THIAZOLOBENZOHETEROCYCLES, PREPARATION AND MEDICINES CONTAINING SAME | RHONE-POULENC RORER S.A. (FR) | 1998-09-03 | — | — | WO | disclosed |