Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | BCL2 | P10415 | 1/20 | 0.31 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HTR1D | P28221 | 1/20 | 0.30 |
| ▸ | HTR1B | P28222 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7524020 | 0.85 | HTR1A (0.51) | HTR1AADRA2ASLC6A2SLC6A4HRH3 | |
| SCHEMBL7524469 | 0.85 | HTR1A (0.51) | HTR1AADRA2ASLC6A2SLC6A4HRH3 | |
| SCHEMBL8372598 | 0.84 | HTR1A (0.50) | HTR1AADRA2ASLC6A2SLC6A4HRH3 | |
| SCHEMBL8371199 | 0.82 | HTR1A (0.49) | HTR1AADRA2ASLC6A2SLC6A4HRH3 | |
| SCHEMBL9122214 | 0.80 | HTR1A (0.50) | HTR1AADRA2ASLC6A2SLC6A4MEN1 | |
| SCHEMBL9120261 | 0.79 | HTR1A (0.58) | HTR1AADRA2ASLC6A2SLC6A4L3MBTL1 | |
| SCHEMBL9123531 | 0.79 | HTR1A (0.49) | HTR1AADRA2ASLC6A2SLC6A4MEN1 | |
| SCHEMBL9120164 | 0.79 | HTR1A (0.49) | HTR1AADRA2ASLC6A2SLC6A4HRH3 | |
| SCHEMBL8370296 | 0.79 | HTR1A (0.47) | HTR1AADRA2ASLC6A2SLC6A4ALDH1A1 | |
| SCHEMBL7336446 | 0.78 | SLC6A2 (0.48) | HTR1AADRA2ASLC6A2SLC6A4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691342-B1 | Benzopyran derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1999-04-28 | — | — | EP | disclosed |
| US-5723484-A | Benzopyran compounds as 5-HT2C receptor antagonists | ADIR ET COMPAGNIE (FR) | 1998-03-03 | — | — | US | disclosed |
| US-5663191-A | PSYCHIATRIC DISEASES, ANXIETY AND ANTIDEPRESSANTS | ADIR ET COMPAGNIE (FR) | 1997-09-02 | — | — | US | disclosed |
| EP-0691342-A1 | Benzopyrane derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-01-10 | — | — | EP | disclosed |