Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 7/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6747214 | 1.00 | KDM1A (0.45) | KDM1ALTA4HHRH3RAB9AALDH1A1 | |
| SCHEMBL6747683 | 0.77 | HRH3 (0.52) | HRH3ALDH1A1 | |
| SCHEMBL6747682 | 0.77 | HRH3 (0.52) | HRH3ALDH1A1 | |
| SCHEMBL25940273 | 0.73 | LTA4H (0.62) | KDM1ALTA4HHRH3KDM4E | |
| SCHEMBL25379342 | 0.72 | LIPE (0.50) | KDM1ALTA4HRAB9AALDH1A1NPC1 | |
| SCHEMBL12315758 | 0.72 | KDM4E (0.63) | KDM1ALTA4HHRH3KDM4E | |
| SCHEMBL25378005 | 0.72 | ALDH1A1 (0.57) | KDM1ALTA4HRAB9AALDH1A1NPC1 | |
| SCHEMBL8850625 | 0.72 | CYP4F2 (0.62) | LTA4HRAB9AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL6880231 | 0.71 | KDM1A (0.42) | KDM1ALTA4HHRH3RAB9AALDH1A1 | |
| SCHEMBL3713953 | 0.71 | POLB (0.66) | HRH3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934941-A1 | BENZOPIPERIDINE DERIVATIVES | Eisai Co., Ltd. (JP) | 1999-08-11 | — | — | EP | disclosed |