Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 2/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | KLK7 | P49862 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2317910 | 0.81 | MAOB (0.44) | MAOBKDM4EALDH1A1CNR1CNR2 | |
| SCHEMBL2317603 | 0.76 | MAOB (0.45) | MAOBKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL2318443 | 0.76 | HSD11B1 (0.44) | MAOBKDM4EALDH1A1MAPTATM | |
| SCHEMBL30065886 | 0.75 | ALDH1A1 (0.61) | MAOBKDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL2315432 | 0.75 | HTR2A (0.49) | MAOBKDM4EALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL6559398 | 0.75 | ALDH1A1 (0.57) | MAOBKDM4EALDH1A1MAPTCNR1 | |
| SCHEMBL2320079 | 0.73 | SIGMAR1 (0.46) | MAOBKDM4EALDH1A1ATM | |
| SCHEMBL2321310 | 0.73 | ALDH1A1 (0.40) | MAOBKDM4EALDH1A1ATMRAD52 | |
| SCHEMBL30953863 | 0.73 | ALDH1A1 (0.40) | MAOBKDM4EALDH1A1ATMRAD52 | |
| SCHEMBL7039475 | 0.73 | KDM4E (0.43) | KDM4EALDH1A1MAPTATMRAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0632033-B1 | NOVEL BENZOPYRAN DERIVATIVE | CHUGAI PHARMACEUTICAL CO LTD (JP) | 1999-04-07 | — | — | EP | disclosed |
| US-5646308-A | POTASSIUM CHANNEL ACTIVATORS USED AS ANTIASTHMATICS, ANTIEPILEPTICS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1997-07-08 | — | — | US | disclosed |
| EP-0632033-A1 | NOVEL BENZOPYRAN DERIVATIVE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1995-01-04 | — | — | EP | disclosed |