Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT1 | P17948 | 3/20 | 0.59 |
| ▸ | FLT4 | P35916 | 3/20 | 0.59 |
| ▸ | KDR | P35968 | 3/20 | 0.59 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.48 |
| ▸ | PYGL | P06737 | 1/20 | 0.47 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL824657 | 0.85 | JAK2 (0.49) | FLT1FLT4KDRNPC1RAB9A | |
| SCHEMBL3787454 | 0.84 | ALDH1A1 (0.50) | SMN1; SMN2PYGLKCNMA1ALOX15KMT2A | |
| SCHEMBL4349861 | 0.83 | KDM4E (0.68) | FLT1FLT4KDRCYP11B2NPC1 | |
| SCHEMBL29833777 | 0.82 | KDM4E (0.67) | FLT1FLT4KDRNPC1RAB9A | |
| SCHEMBL4154496 | 0.82 | KDM4E (0.67) | FLT1FLT4KDRNPC1RAB9A | |
| SCHEMBL3814303 | 0.81 | P2RX1 (0.53) | NPC1RAB9AKCNMA1ALOX15POLB | |
| SCHEMBL24997807 | 0.80 | FLT1 (0.55) | FLT1FLT4KDRCYP11B2NPC1 | |
| SCHEMBL4597516 | 0.80 | FLT1 (0.55) | FLT1FLT4KDRCYP11B2NPC1 | |
| SCHEMBL328219 | 0.80 | SMN1; SMN2 (0.56) | FLT1FLT4KDRNPC1RAB9A | |
| SCHEMBL250256 | 0.79 | FLT1 (0.53) | FLT1FLT4KDRCYP11B2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022000443-A1 | METHODS AND COMPOSITIONS FOR TARGETING TREGS USING CCR8 INHIBITORS | Nanjing Immunophage Biotech Co., Ltd. (CN) | 2022-01-06 | — | — | WO | disclosed |
| CN-110037021-A | A kind of acaricidal miticide composition of Synergistic type of class containing biphenyl | 侨昌现代农业有限公司 | 2019-07-23 | — | — | CN | disclosed |
| EP-0636625-B1 | Tricyclic diazepines vasopressin and oxytocin antagonists | AMERICAN CYANAMID CO (US) | 1999-01-27 | — | — | EP | disclosed |