Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TRPM8 | Q7Z2W7 | 11/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3043563 | 0.78 | NPC1 (0.37) | SMN1; SMN2TRPM8RAB9A | |
| SCHEMBL2619292 | 0.75 | SMN1; SMN2 (0.68) | LMNASMN1; SMN2RAB9AL3MBTL1 | |
| SCHEMBL15543197 | 0.75 | TRPM8 (0.47) | LMNASMN1; SMN2TRPM8 | |
| SCHEMBL5507744 | 0.73 | LMNA (0.64) | LMNASMN1; SMN2TRPM8CHRM2CHRM3 | |
| SCHEMBL2053938 | 0.72 | CNR2 (0.40) | LMNASMN1; SMN2TRPM8ADORA2ARAB9A | |
| SCHEMBL5507759 | 0.71 | LMNA (0.53) | LMNASMN1; SMN2TRPM8ADORA2ARAB9A | |
| SCHEMBL13892312 | 0.70 | ABCG2 (0.58) | LMNASMN1; SMN2TRPM8ADORA2ARAB9A | |
| SCHEMBL13947396 | 0.69 | SMN1; SMN2 (0.54) | LMNASMN1; SMN2TRPM8RAB9AL3MBTL1 | |
| SCHEMBL14350435 | 0.69 | HDAC6 (0.53) | LMNASMN1; SMN2 | |
| SCHEMBL8324448 | 0.68 | P2RX7 (0.38) | SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934940-A1 | CYTOKINE PRODUCTION INHIBITORS, TRIAZEPINE COMPOUNDS, AND INTERMEDIATES THEREOF | Japan Tobacco Inc. (JP) | 1999-08-11 | — | — | EP | disclosed |