Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PTPRC | P08575 | 3/20 | 0.38 |
| ▸ | S100A4 | P26447 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13292077 | 0.78 | PTPRC (0.52) | ALDH1A1MAPTTDP1IDO1MEN1 | |
| SCHEMBL13544020 | 0.74 | TDP1 (0.56) | ALDH1A1MAPTTDP1IDO1MEN1 | |
| SCHEMBL2404650 | 0.71 | ALDH1A1 (0.50) | ALDH1A1MAPTTDP1MEN1KMT2A | |
| SCHEMBL13292086 | 0.71 | TDP1 (0.65) | ALDH1A1MAPTTDP1IDO1MEN1 | |
| SCHEMBL158311 | 0.71 | ALDH1A1 (1.00) | ALDH1A1MAPTTDP1MEN1KMT2A | |
| SCHEMBL29661178 | 0.71 | ALDH1A1 (1.00) | ALDH1A1MAPTTDP1MEN1KMT2A | |
| SCHEMBL30718118 | 0.71 | KMT2A (0.53) | TDP1KMT2AKDM4E | |
| SCHEMBL8660096 | 0.71 | PTGS2 (0.35) | TDP1MEN1KMT2AHTTLMNA | |
| SCHEMBL2333513 | 0.71 | KMT2A (0.53) | TDP1KMT2AKDM4E | |
| SCHEMBL4073817 | 0.71 | DYRK1A (0.35) | TDP1IDO1KMT2APTPRCS100A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5959116-A | 5-NITRO PYRIDINE-2,3-DICARBOXYLIC ACID ESTER CHEMICAL INTERMEDIATES MADE BY REACTING THE N-OXIDES OF PYRIDINE-2,3-DICARBOXYLIC ACID ESTERS WITH NITRIC ACID OR SODIUM NITRATE, THEN REMOVING THE N-OXIDE GROUP | BASF AKTIENGESELLSCHAFT (DE) | 1999-09-28 | — | — | US | disclosed |
| US-5571774-A | HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1996-11-05 | — | — | US | disclosed |