Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 6/20 | 0.54 |
| ▸ | MMP13 | P45452 | 6/20 | 0.54 |
| ▸ | MMP12 | P39900 | 4/20 | 0.54 |
| ▸ | MMP1 | P03956 | 4/20 | 0.54 |
| ▸ | MMP7 | P09237 | 2/20 | 0.54 |
| ▸ | MMP9 | P14780 | 5/20 | 0.50 |
| ▸ | MMP2 | P08253 | 3/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.48 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6268870 | 1.00 | MMP8 (0.54) | MMP8MMP13MMP12MMP1MMP7 | |
| SCHEMBL6266747 | 1.00 | MMP8 (0.54) | MMP8MMP13MMP12MMP1MMP7 | |
| SCHEMBL6268860 | 1.00 | MMP8 (0.54) | MMP8MMP13MMP12MMP1MMP7 | |
| SCHEMBL6266744 | 1.00 | MMP8 (0.54) | MMP8MMP13MMP12MMP1MMP7 | |
| SCHEMBL6271220 | 0.93 | MMP13 (0.57) | MMP8MMP13MMP12MMP1MMP7 | |
| SCHEMBL6802716 | 0.93 | MMP13 (0.57) | MMP8MMP13MMP12MMP1MMP7 | |
| SCHEMBL27539860 | 0.92 | MMP13 (0.49) | MMP8MMP13MMP12MMP1MMP7 | |
| SCHEMBL6401384 | 0.86 | TAAR1 (0.52) | MMP8MMP13MMP12MMP1MMP7 | |
| SCHEMBL6276800 | 0.79 | MMP13 (0.49) | MMP8MMP13MMP12MMP1MMP9 | |
| SCHEMBL6732244 | 0.78 | MMP9 (0.52) | MMP8MMP13MMP12MMP1MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004073599-A2 | INHIBITORS OF HEPATITIS C VIRUS, COMPOSITIONS AND TREATMENTS USING THE SAME | PFIZER INC. (US) | 2004-09-02 | — | — | WO | disclosed |