Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TYMS | P04818 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7703768 | 0.91 | ALDH1A1 (0.47) | ALDH1A1HTTSMN1; SMN2TYMSPTPN1 | |
| SCHEMBL7703754 | 0.77 | TYMS (0.41) | ALDH1A1HTTSMN1; SMN2TYMSLMNA | |
| SCHEMBL7709415 | 0.74 | TYMS (0.58) | TYMSRAD52KMT2A | |
| SCHEMBL7706740 | 0.70 | KMT2A (0.47) | ALDH1A1HTTSMN1; SMN2TYMSPOLB | |
| SCHEMBL7709368 | 0.68 | MAPT (0.56) | ALDH1A1HTTPTPN1POLBLMNA | |
| SCHEMBL7709465 | 0.67 | POLB (0.51) | ALDH1A1HTTSMN1; SMN2TYMSPOLB | |
| SCHEMBL17726769 | 0.65 | TYMS (0.53) | ALDH1A1SMN1; SMN2TYMSMEN1KMT2A | |
| SCHEMBL15119613 | 0.65 | MAOA (0.42) | ALDH1A1TYMSRAD52 | |
| SCHEMBL8461080 | 0.65 | KMT2A (0.55) | ALDH1A1HTTPOLBLMNARAD52 | |
| SCHEMBL9080103 | 0.64 | ALOX5 (0.44) | ALDH1A1SMN1; SMN2TYMSPOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0939754-A2 | N-OXY-NAPHTHALIMIDES AS ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1999-09-08 | — | — | EP | disclosed |
| WO-1998019648-A2 | N-OXY-NAPHTHALIMIDES AS ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1998-05-14 | — | — | WO | disclosed |