Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 16/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8321030 | 0.80 | HDAC1 (0.44) | HDAC1HDAC8HDAC3HDAC4HDAC2 | |
| SCHEMBL22641730 | 0.80 | MAPT (0.48) | HDAC1HDAC8HDAC3HDAC4HDAC2 | |
| SCHEMBL8325208 | 0.79 | HDAC1 (0.47) | HDAC1HDAC8HDAC3HDAC4HDAC2 | |
| SCHEMBL8326119 | 0.79 | HDAC1 (0.46) | HDAC1HDAC8HDAC3HDAC4HDAC2 | |
| SCHEMBL22641632 | 0.76 | HDAC3 (0.50) | HDAC1HDAC8HDAC3HDAC4HDAC2 | |
| SCHEMBL8324552 | 0.76 | LMNA (0.47) | HDAC1HDAC8HDAC3HDAC4HDAC2 | |
| SCHEMBL22579255 | 0.75 | MAPT (0.42) | HDAC1HDAC4MAPTLMNAKDM4E | |
| SCHEMBL22641675 | 0.74 | MAPT (0.47) | HDAC1HDAC8HDAC3HDAC4HDAC2 | |
| SCHEMBL15341321 | 0.73 | TRPV1 (0.46) | HDAC1HDAC8HDAC3HDAC4HDAC2 | |
| SCHEMBL15341322 | 0.72 | HDAC8 (0.43) | HDAC1HDAC8HDAC3HDAC4HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004063169-A1 | HYDROXAMID ACID DERIVATIVES AS HISTONE DEACETYLASE (HDAC) INHIBITORS | ASTELLAS PHARMA INC. (JP) | 2004-07-29 | — | — | WO | disclosed |