SCHEMBL8318692

SCHEMBL8318692

CC(C)(C)NS(=O)(=O)c1cccnc1Cl

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.47
NSD2 O96028 2/20 0.45
ACLY P53396 1/20 0.44
ALOX5AP P20292 7/20 0.44
FEN1 P39748 7/20 0.44
CNR2 P34972 1/20 0.41
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
KDM4E B2RXH2 1/20 0.41
NPC1 O15118 1/20 0.41
LMNA P02545 1/20 0.41
MAPT P10636 1/20 0.41
HPGD P15428 1/20 0.41
RAB9A P51151 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
NFE2L2 Q16236 2/20 0.41
EGFR P00533 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14676598 0.83 ACLY (0.48) ALDH1A1ACLYCNR2MEN1KMT2A
SCHEMBL2201120 0.82 FTO (0.50) ALDH1A1ACLYMEN1KMT2ANPC1
SCHEMBL14680719 0.82 ACLY (0.44) ALDH1A1ACLYALOX5APFEN1CNR2
SCHEMBL27933654 0.79 NSD2 (0.45) ALDH1A1NSD2ALOX5APFEN1MEN1
SCHEMBL9037582 0.79 ALOX5AP (0.49) ALDH1A1NSD2ALOX5APFEN1MEN1
SCHEMBL8114615 0.78 ALDH1A1 (0.46) ALDH1A1NSD2MEN1KMT2AKDM4E
SCHEMBL25754551 0.77 NSD2 (0.44) ALDH1A1NSD2ALOX5APFEN1MEN1
SCHEMBL15625457 0.77 ALDH1A1 (0.59) ALDH1A1ACLYMEN1KMT2ALMNA
SCHEMBL14247455 0.77 SLC22A12 (0.51) ALDH1A1NSD2ALOX5APFEN1NFE2L2
SCHEMBL20269260 0.76 ALOX5AP (0.43) ACLYALOX5APFEN1CNR2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5869428-A CONTROLLING WEEDS ISHIHARA SANGYO KAISHA LTD. (JP) 1999-02-09 US disclosed
EP-0733629-A1 Pyridonesulfonylurea compounds, process for their production and herbicides containing them ISHIHARA SANGYO KAISHA, LTD. (JP) 1996-09-25 EP disclosed