Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | GFER | P55789 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8320341 | 0.85 | ADRB1 (0.61) | MAPTALDH1A1GFERSMN1; SMN2KMT2A | |
| SCHEMBL8319638 | 0.85 | MAPT (0.65) | MAPTALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL8318825 | 0.83 | MAPT (0.59) | MAPTALDH1A1GFERSMN1; SMN2KMT2A | |
| SCHEMBL8264511 | 0.82 | MAPT (0.68) | MAPTALDH1A1GFERSMN1; SMN2KMT2A | |
| SCHEMBL30228205 | 0.81 | MEN1 (0.69) | MAPTALDH1A1GFERSMN1; SMN2KMT2A | |
| SCHEMBL25556655 | 0.79 | GAA (0.64) | MAPTALDH1A1GFERSMN1; SMN2KMT2A | |
| SCHEMBL25758199 | 0.79 | MAPT (0.55) | MAPTALDH1A1GFERSMN1; SMN2KMT2A | |
| SCHEMBL2984679 | 0.78 | ADRB1 (0.73) | MAPTALDH1A1GFERSMN1; SMN2KMT2A | |
| SCHEMBL8263576 | 0.78 | MAPT (0.62) | MAPTALDH1A1GFERSMN1; SMN2KMT2A | |
| SCHEMBL13034799 | 0.76 | MAPT (0.68) | MAPTALDH1A1GFERSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5945421-A | TREATING PSYCHOSIS AND SCHIZOPHRENIA | WARNER-LAMBERT COMPANY (US) | 1999-08-31 | — | — | US | disclosed |