Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | RAD52 | P43351 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 3/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8318822 | 0.85 | MAPT (0.62) | ADRB1MAPTALDH1A1GFERHTT | |
| SCHEMBL8320347 | 0.82 | ADRB1 (0.63) | ADRB1MAPTGAAALDH1A1GFER | |
| SCHEMBL24140572 | 0.81 | ADRB1 (0.68) | ADRB1MAPTGAAALDH1A1GFER | |
| SCHEMBL3539353 | 0.81 | ADRB1 (0.68) | ADRB1MAPTGAAALDH1A1GFER | |
| SCHEMBL10702610 | 0.80 | ADRB1 (0.61) | ADRB1MAPTGAAALDH1A1GFER | |
| SCHEMBL8390975 | 0.79 | ADRB1 (0.66) | ADRB1MAPTGAAALDH1A1GFER | |
| SCHEMBL22818552 | 0.79 | ADRB1 (0.66) | ADRB1MAPTGAAALDH1A1GFER | |
| SCHEMBL2021224 | 0.78 | MAPT (0.66) | ADRB1MAPTGAAALDH1A1GFER | |
| SCHEMBL25787603 | 0.78 | MAPT (0.61) | ADRB1MAPTGAAALDH1A1GFER | |
| SCHEMBL13153256 | 0.77 | ADRB1 (0.58) | ADRB1MAPTGAAALDH1A1GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5945421-A | TREATING PSYCHOSIS AND SCHIZOPHRENIA | WARNER-LAMBERT COMPANY (US) | 1999-08-31 | — | — | US | disclosed |