Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.65 |
| ▸ | LMNA | P02545 | 4/20 | 0.65 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8318822 | 0.85 | MAPT (0.62) | MAPTSMN1; SMN2LMNAALOX12L3MBTL1 | |
| SCHEMBL5618735 | 0.82 | MAPT (0.67) | MAPTSMN1; SMN2LMNAALOX12L3MBTL1 | |
| SCHEMBL9830834 | 0.81 | ADRB1 (0.68) | MAPTSMN1; SMN2LMNAALOX12L3MBTL1 | |
| SCHEMBL423400 | 0.80 | MAPT (0.65) | MAPTSMN1; SMN2LMNAALOX12L3MBTL1 | |
| SCHEMBL27918171 | 0.79 | MAPT (0.69) | MAPTSMN1; SMN2LMNAALOX12L3MBTL1 | |
| SCHEMBL7715055 | 0.79 | ADRB1 (0.66) | MAPTSMN1; SMN2LMNAALOX12L3MBTL1 | |
| SCHEMBL8320134 | 0.79 | NOTUM (0.52) | MAPTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL631834 | 0.78 | MAPT (0.68) | MAPTSMN1; SMN2LMNAALOX12L3MBTL1 | |
| SCHEMBL27953332 | 0.78 | MAPT (0.68) | MAPTSMN1; SMN2LMNAALOX12L3MBTL1 | |
| SCHEMBL5543934 | 0.78 | MAPT (0.68) | MAPTSMN1; SMN2LMNAALOX12L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5945421-A | TREATING PSYCHOSIS AND SCHIZOPHRENIA | WARNER-LAMBERT COMPANY (US) | 1999-08-31 | — | — | US | disclosed |