Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 18/20 | 0.41 |
| ▸ | GAA | P10253 | 10/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | HPGD | P15428 | 5/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 17/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 6/20 | 0.38 |
| ▸ | HPN | P05981 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | IDE | P14735 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8317948 | 0.78 | GAA (0.56) | KMT2AGAAALDH1A1KDM4EHPGD | |
| SCHEMBL17916662 | 0.75 | ALDH1A1 (0.57) | KMT2AGAAALDH1A1KDM4EHPGD | |
| SCHEMBL10607517 | 0.74 | KMT2A (0.36) | KMT2AGAAALDH1A1KDM4EHPGD | |
| SCHEMBL13012832 | 0.68 | KMT2A (0.44) | KMT2AGAAALDH1A1KDM4EHPGD | |
| SCHEMBL16504030 | 0.67 | GAA (0.50) | KMT2AGAAALDH1A1KDM4EHPGD | |
| SCHEMBL10078299 | 0.67 | MEN1 (0.55) | KMT2AGAAALDH1A1KDM4EHPGD | |
| SCHEMBL19262253 | 0.66 | MEN1 (0.50) | KMT2AGAAALDH1A1KDM4EHPGD | |
| SCHEMBL10606300 | 0.62 | GAA (0.45) | KMT2AGAAALDH1A1KDM4EHPGD | |
| SCHEMBL28489824 | 0.62 | KMT2A (0.55) | KMT2AGAAALDH1A1KDM4EHPGD | |
| SCHEMBL13807152 | 0.62 | PTPN1 (0.38) | KMT2AGAAMEN1MAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0932603-A1 | METHOD FOR PRODUCING 1,8-DIAMINONAPHTHALINES AND THEIR 2,3-DIHYDROPERIMIDINE DERIVATIVES | BAYER AG (DE) | 1999-08-04 | — | — | EP | disclosed |
| WO-1998015533-A1 | METHOD FOR PRODUCING 1,8-DIAMINONAPHTHALINES AND THEIR 2,3-DIHYDROPERIMIDINE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-04-16 | — | — | WO | disclosed |