Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | NCF1 | P14598 | 1/20 | 0.42 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 2/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CHRNA2 | Q15822 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.37 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | HTR3B | O95264 | 1/20 | 0.37 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3976295 | 0.82 | CHRNB2 (0.55) | CHRNA7CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL1579434 | 0.82 | CHRNB2 (0.55) | CHRNA7CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL18913839 | 0.82 | CHRNB2 (0.55) | CHRNA7CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL470846 | 0.82 | CHRNB2 (0.55) | CHRNA7CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL15217034 | 0.81 | CHRNB2 (0.61) | CHRNA7CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL5734703 | 0.81 | KDM4E (0.41) | MAPTGAAHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL27673502 | 0.81 | CHRNB2 (0.53) | CHRNA7CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL6026785 | 0.81 | ADRB1 (0.43) | CHRNA7CHRNB2CHRNA4CHRNB4CHRNA3 | |
| Hydrochloric Acid SCHEMBL1722775 | 0.81 | CHRNB2 (0.53) | CHRNA7CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL659344 | 0.80 | MAOA (0.49) | CHRNA7HTR3EHTR3BHTR3AHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081912-A2 | HETEROCYCLES AND USES THEREOF | KUMQUAT BIOSCIENCES INC. (US) | 2022-04-21 | — | — | WO | disclosed |
| CN-101234965-B | Method for producing dialkyl carbonate | CHINA PETROCHEMICAL DEV CORP | 2011-04-06 | — | — | CN | disclosed |
| CN-101234965-A | Method for producing dialkyl carbonate | CHINA PETROCHEMICAL DEV CORP (CN) | 2008-08-06 | — | — | CN | disclosed |
| EP-0925302-A1 | PALLADIUM CATALYZED INDOLIZATION | Merck & Co., Inc. (US) | 1999-06-30 | — | — | EP | disclosed |
| WO-1998006725-A1 | PALLADIUM CATALYZED INDOLIZATION | MERCK & CO., INC. (US) | 1998-02-19 | — | — | WO | disclosed |