Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 8/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11969337 | 1.00 | TSHR (0.42) | TSHRTHRBDNM1ALDH1A1LMNA | |
| SCHEMBL422635 | 1.00 | TSHR (0.42) | TSHRTHRBDNM1ALDH1A1LMNA | |
| SCHEMBL30239111 | 1.00 | TSHR (0.42) | TSHRTHRBDNM1ALDH1A1LMNA | |
| SCHEMBL30238622 | 1.00 | TSHR (0.42) | TSHRTHRBDNM1ALDH1A1LMNA | |
| SCHEMBL6246621 | 1.00 | TSHR (0.42) | TSHRTHRBDNM1ALDH1A1LMNA | |
| SCHEMBL28341834 | 1.00 | TSHR (0.42) | TSHRTHRBDNM1ALDH1A1LMNA | |
| SCHEMBL11969287 | 1.00 | TSHR (0.42) | TSHRTHRBDNM1ALDH1A1LMNA | |
| SCHEMBL258804 | 1.00 | TSHR (0.42) | TSHRTHRBDNM1ALDH1A1LMNA | |
| SCHEMBL422241 | 0.89 | DNM1 (0.33) | TSHRTHRBDNM1LMNA | |
| SCHEMBL15182784 | 0.89 | ALDH1A1 (0.30) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0693314-B1 | Chromatography using silicon dioxide based adsorbents. | UETIKON CHEMIE AG (CH) | 2001-09-26 | — | — | EP | disclosed |
| EP-0574642-B1 | Procedure for the preparation of powders and suspensions of amorphous silicon dioxide microspheres | UETIKON CHEMIE AG (CH) | 1998-10-28 | — | — | EP | disclosed |
| US-5762803-A | Silicon dioxide based microspheres for rapid chromatographic separation of biomolecules | CU CHEMIE UETIKON AG (CH) | 1998-06-09 | — | — | US | disclosed |
| EP-0693314-A1 | Silicon dioxide based adsorbents for chromatography | CU CHEMIE UETIKON AG (CH) | 1996-01-24 | — | — | EP | disclosed |
| EP-0574642-A1 | Procedure for the preparation of powders and suspensions of amorphous silicon dioxide microspheres | CU CHEMIE UETIKON AG (CH) | 1993-12-22 | — | — | EP | disclosed |