SCHEMBL258804

SCHEMBL258804

CCCCCCCCCCCCCCCCCC[Si](C)(C)N(C)C

nearest known ligand 0.42

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.42
THRB P10828 1/20 0.42
DNM1 Q05193 8/20 0.42
ALDH1A1 P00352 3/20 0.33
LMNA P02545 2/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
HSD17B10 Q99714 1/20 0.33
SLC22A1 O15245 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11969337 1.00 TSHR (0.42) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL422635 1.00 TSHR (0.42) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL30239111 1.00 TSHR (0.42) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL30238622 1.00 TSHR (0.42) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL6246621 1.00 TSHR (0.42) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL28341834 1.00 TSHR (0.42) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL11969287 1.00 TSHR (0.42) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL7922841 1.00 TSHR (0.42) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL422241 0.89 DNM1 (0.33) TSHRTHRBDNM1LMNA
SCHEMBL15182784 0.89 ALDH1A1 (0.30) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 122 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4354134-A2 SORBENTS, DEVICES, KITS AND METHODS USEFUL FOR BIOLOGICAL SAMPLE TREATMENT Waters Technologies Corporation (US) 2024-04-17 EP claimed
US-11670512-B2 Selective deposition on silicon containing surfaces VERSUM MATERIALS US, LLC (US) 2023-06-06 US claimed
US-20220280909-A1 SORBENT PARTICLES FOR SAMPLE TREATMENT WATERS TECHNOLOGIES CORPORATION (US) 2022-09-08 US claimed
US-11376561-B2 Sorbent particles for sample treatment WATERS TECHNOLOGIES CORPORATION (US) 2022-07-05 US claimed
CN-110612364-B Selective deposition on silicon-containing surfaces 弗萨姆材料美国有限责任公司 2022-04-05 CN claimed
EP-3860755-A1 SORBENTS, DEVICES, KITS AND METHODS USEFUL FOR BIOLOGICAL SAMPLE TREATMENT Waters Technologies Corporation (US) 2021-08-11 EP claimed
CN-113164910-A Adsorbents, devices, kits and methods useful for biological sample processing 沃特世科技公司 2021-07-23 CN claimed
US-20210118684-A1 SELECTIVE DEPOSITION ON SILICON CONTAINING SURFACES VERSUM MATERIALS US, LLC 2021-04-22 US claimed
WO-2020072668-A1 SORBENTS, DEVICES, KITS AND METHODS USEFUL FOR BIOLOGICAL SAMPLE TREATMENT WATERS TECHNOLOGIES CORPORATION (US) 2020-04-09 WO claimed
US-20200101437-A1 SORBENTS, DEVICES, KITS AND METHODS USEFUL FOR SAMPLE TREATMENT WATERS TECHNOLOGIES CORPORATION 2020-04-02 US claimed
CN-110612364-A Selective deposition on silicon-containing surfaces 弗萨姆材料美国有限责任公司 2019-12-24 CN claimed
WO-2018170382-A1 SELECTIVE DEPOSITION ON SILICON CONTAINING SURFACES VERSUM MATERIALS US, LLC (US) 2018-09-20 WO claimed
US-9289747-B2 Nanocomposites and their application as monolith columns WATERS TECHNOLOGIES CORPORATION (US) 2016-03-22 US claimed
US-20150021774-A1 Molecular Self-Assembly in Substrate Processing INTERMOLECULAR INC (US) 2015-01-22 US claimed
US-8486282-B2 Acid chemistries and methodologies for texturing transparent conductive oxide materials INTERMOLECULAR, INC. (US) 2013-07-16 US claimed
US-8372759-B2 Molecular self-assembly in substrate processing INTERMOLECULAR, INC. (US) 2013-02-12 US claimed
US-20110163424-A1 Molecular Self-Assembly In Substrate Processing INTERMOLECULAR, INC. (US) 2011-07-07 US claimed
US-20080113178-A1 prevention of diffusion of foreign material through the exposed pores of porous dielectric by sealing; exposing the substrate to a polymizerable organosilane to form a bonding layer of polysiloxanes or polysilsesquioxanes; pre-cleaning; forming a copper interconnection; produce nanometer size INTERMOLECULAR, INC. 2008-05-15 US claimed
US-20070141325-A1 Novel nanocomposites and their application as monolith columns WATERS INVESTMENTS LIMITED (US) 2007-06-21 US claimed
WO-2004105910-A2 NOVEL NANOCOMPOSITES AND THEIR APPLICATION AS MONOLITH COLUMNS WATERS INVESTMENTS LIMITED (US) 2004-12-09 WO claimed