Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2811130 | 0.78 | CA12 (0.48) | MAPTALDH1A1RECQLUSP2ALOX15 | |
| SCHEMBL7632372 | 0.72 | ALDH1A1 (0.39) | MAPTALDH1A1RECQLUSP2ALOX15 | |
| SCHEMBL31026771 | 0.71 | COXFA4 (0.50) | MAPTALDH1A1RECQLUSP2ALOX15 | |
| SCHEMBL6210404 | 0.71 | COXFA4 (0.50) | MAPTALDH1A1RECQLUSP2ALOX15 | |
| SCHEMBL227343 | 0.69 | RAB9A (0.50) | MAPTALDH1A1RECQLSMN1; SMN2CA12 | |
| SCHEMBL17888591 | 0.68 | SMN1; SMN2 (0.43) | ALDH1A1RECQLALOX15SMN1; SMN2CA12 | |
| SCHEMBL1602359 | 0.68 | RAB9A (0.49) | ALDH1A1RECQLSMN1; SMN2CA12CA1 | |
| SCHEMBL13537289 | 0.68 | NPC1 (0.49) | ALDH1A1RECQLALOX15SMN1; SMN2CA12 | |
| SCHEMBL31058820 | 0.68 | RAB9A (0.49) | ALDH1A1RECQLSMN1; SMN2CA12CA1 | |
| SCHEMBL17276324 | 0.67 | PDK2 (0.40) | MAPTALDH1A1RECQLSMN1; SMN2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888327-A1 | BENZOPYRAN DERIVATIVES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION | LABORATORIOS MENARINI S.A. (ES) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997034885-A1 | BENZOPYRAN DERIVATIVES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION | LABORATORIOS MENARINI S.A. (ES) | 1997-09-25 | — | — | WO | disclosed |