Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.54 |
| ▸ | GRM8 | O00222 | 1/20 | 0.52 |
| ▸ | GRM6 | O15303 | 1/20 | 0.52 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8319206 | 1.00 | ALDH1A1 (0.60) | ALDH1A1TSHRALOX15PTPN7MEN1 | |
| SCHEMBL6831673 | 0.85 | ALDH1A1 (0.64) | ALDH1A1TSHRALOX15PTPN7MEN1 | |
| SCHEMBL8088670 | 0.83 | GPR174 (0.52) | ALDH1A1TSHRMAPTGRM8GRM6 | |
| SCHEMBL339492 | 0.82 | ALOX15 (0.81) | ALDH1A1TSHRALOX15PTPN7MEN1 | |
| SCHEMBL23053351 | 0.81 | AKR1C3 (0.55) | ALDH1A1TSHRSMN1; SMN2LMNAMAPK1 | |
| SCHEMBL9195223 | 0.81 | AKR1C3 (0.55) | ALDH1A1TSHRSMN1; SMN2LMNAMAPK1 | |
| SCHEMBL9427862 | 0.81 | AKR1C3 (0.55) | ALDH1A1TSHRSMN1; SMN2LMNAMAPK1 | |
| SCHEMBL9142660 | 0.80 | GAA (0.53) | ALDH1A1TSHRSMN1; SMN2LMNAMAPK1 | |
| SCHEMBL15942681 | 0.80 | ALOX15 (0.66) | ALDH1A1TSHRALOX15PTPN7MEN1 | |
| SCHEMBL31265587 | 0.80 | ALDH1A1 (0.58) | ALDH1A1TSHRALOX15PTPN7MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6128499-A | — | — | None | — | — | JP | disclosed |
| EP-0559345-B1 | Polycyclic dyes | BASF AG (DE) | 1999-05-06 | — | — | EP | disclosed |
| EP-0560499-B1 | Process for the preparation of polycyclic dyes | BASF AG (DE) | 1997-07-09 | — | — | EP | disclosed |
| US-5422415-A | Benzofuran derivative, phenolic antioxidant, secondary amine antioxidant; foams | CIBA-GEIGY CORPORATION (US) | 1995-06-06 | — | — | US | disclosed |
| US-5360919-A | Quinone and hydroquinone dyes | ZENECA LIMITED (GB) | 1994-11-01 | — | — | US | disclosed |
| US-5356966-A | Stabilizing organic material against oxidative, thermal or light iinduced degradation | CIBA-GEIGY CORPORATION (US) | 1994-10-18 | — | — | US | disclosed |
| US-5319109-A | Polycyclic dyes | ZENECA LIMITED (GB) | 1994-06-07 | — | — | US | disclosed |
| JP-H06128499-A | POLYCYCLIC DYE | ZENECA LTD | 1994-05-10 | — | — | JP | disclosed |
| US-5308899-A | Benzofuranone derivative, phenolic and secondary amine antioxidants | CIBA-GEIGY CORPORATION (US) | 1994-05-03 | — | — | US | disclosed |
| EP-0574148-A1 | Polycyclic dyes | ZENECA LIMITED (GB) | 1993-12-15 | — | — | EP | disclosed |
| EP-0560499-A1 | Polycyclic dyes | ZENECA LIMITED (GB) | 1993-09-15 | — | — | EP | disclosed |
| EP-0559345-A1 | Polycyclic dyes | ZENECA LIMITED (GB) | 1993-09-08 | — | — | EP | disclosed |
| EP-0146269-B1 | HETERO-POLYCYCLIC AROMATIC COMPOUND | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-01-03 | — | — | EP | disclosed |
| EP-0294029-A2 | Hetero-polycyclic aromatic compounds | ZENECA LIMITED (GB) | 1988-12-07 | — | — | EP | disclosed |
| US-4650882-A | Dyes having two 5-membered lactone rings fused to a central cyclohexa-1.4-diene nucleus | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-03-17 | — | — | US | disclosed |
| EP-0146269-A2 | Hetero-polycyclic aromatic compound | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-06-26 | — | — | EP | disclosed |