Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6991711 | 0.79 | HRH1 (0.47) | MAPK1ALDH1A1CYP3A4CYP2C9MEN1 | |
| SCHEMBL6999204 | 0.78 | MAPK1 (0.46) | MAPK1ALDH1A1CYP3A4CYP2C9MEN1 | |
| SCHEMBL27452559 | 0.77 | MAPK1 (0.46) | MAPK1ALDH1A1CYP3A4CYP2C9MEN1 | |
| SCHEMBL8810255 | 0.77 | ALDH1A1 (0.38) | MAPK1ALDH1A1CYP3A4CYP2C9MEN1 | |
| Fluorobenzene SCHEMBL27404940 | 0.77 | ALDH1A1 (0.45) | MAPK1ALDH1A1CYP3A4CYP2C9MEN1 | |
| SCHEMBL8318836 | 0.75 | MAPK1 (0.39) | MAPK1ALDH1A1MEN1KMT2APOLB | |
| Fluorobenzene SCHEMBL27382447 | 0.73 | ALDH1A1 (0.43) | MAPK1ALDH1A1CYP3A4CYP2C9MEN1 | |
| SCHEMBL7956133 | 0.72 | KDM4E (0.43) | MAPK1ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL6998261 | 0.71 | SMN1; SMN2 (0.46) | MAPK1ALDH1A1CYP3A4CYP2C9MEN1 | |
| SCHEMBL6992507 | 0.71 | ALDH1A1 (0.45) | MAPK1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0920425-A1 | SUBSTITUTED 4-(1H-BENZIMIDAZOL-2-YL-AMINO)PIPERIDINES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES | HOECHST MARION ROUSSEL, INC. (US) | 1999-06-09 | — | — | EP | disclosed |
| WO-1997019074-A1 | SUBSTITUTED 4-(1H-BENZIMIDAZOL-2-YL-AMINO)PIPERIDINES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES | HOECHST MARION ROUSSEL, INC. (US) | 1997-05-29 | — | — | WO | disclosed |