Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8810255 | 0.89 | ALDH1A1 (0.38) | MAPK1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL6998325 | 0.81 | HRH1 (0.45) | MAPK1MEN1KMT2AKDM4EALDH1A1 | |
| Fluorobenzene SCHEMBL27405662 | 0.80 | HTT (0.44) | MAPK1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL6998268 | 0.80 | MAPK1 (0.41) | MAPK1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL27404103 | 0.79 | MAPK1 (0.40) | MAPK1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL8319786 | 0.75 | MAPK1 (0.43) | MAPK1MEN1KMT2AALDH1A1HCRTR1 | |
| SCHEMBL6996096 | 0.75 | ALDH1A1 (0.44) | MAPK1KDM4EALDH1A1HTTL3MBTL1 | |
| SCHEMBL7981028 | 0.75 | TP53 (0.39) | MAPK1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL6992505 | 0.74 | L3MBTL1 (0.43) | MAPK1MEN1KMT2AALDH1A1HTT | |
| SCHEMBL6994509 | 0.73 | KMT2A (0.37) | MAPK1MEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0920425-A1 | SUBSTITUTED 4-(1H-BENZIMIDAZOL-2-YL-AMINO)PIPERIDINES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES | HOECHST MARION ROUSSEL, INC. (US) | 1999-06-09 | — | — | EP | disclosed |
| WO-1997019074-A1 | SUBSTITUTED 4-(1H-BENZIMIDAZOL-2-YL-AMINO)PIPERIDINES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES | HOECHST MARION ROUSSEL, INC. (US) | 1997-05-29 | — | — | WO | disclosed |