Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8318836 | 0.89 | MAPK1 (0.39) | ALDH1A1MAPK1KDM4EHTTMEN1 | |
| SCHEMBL7961446 | 0.80 | HRH1 (0.44) | ALDH1A1MAPK1KDM4EHTTMEN1 | |
| SCHEMBL7958360 | 0.79 | MEN1 (0.40) | ALDH1A1MAPK1KDM4EHTTMEN1 | |
| SCHEMBL8319786 | 0.77 | MAPK1 (0.43) | ALDH1A1MAPK1MEN1KMT2AHCRTR1 | |
| SCHEMBL7947370 | 0.74 | ALDH1A1 (0.45) | ALDH1A1KDM4EHTTMEN1KMT2A | |
| SCHEMBL7947626 | 0.74 | KDM4E (0.39) | ALDH1A1KDM4EHTTMEN1KMT2A | |
| SCHEMBL7956429 | 0.73 | MEN1 (0.39) | ALDH1A1KDM4EHTTMEN1KMT2A | |
| SCHEMBL7627714 | 0.72 | MAPK1 (0.41) | ALDH1A1MAPK1KDM4EHTTMEN1 | |
| SCHEMBL7954527 | 0.71 | KDM4E (0.41) | ALDH1A1KDM4EHTTMEN1KMT2A | |
| SCHEMBL6998325 | 0.71 | HRH1 (0.45) | ALDH1A1MAPK1KDM4EHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0777666-A1 | NOVEL SUBSTITUTED PIPERIDINES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES | MERRELL PHARMACEUTICALS INC. (US) | 1997-06-11 | — | — | EP | disclosed |