Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8324428 | 0.84 | RECQL (0.51) | ALDH1A1RECQLMAPTHPGDTDP1 | |
| SCHEMBL8666821 | 0.77 | RECQL (0.54) | ALDH1A1RECQLMAPTHPGDTDP1 | |
| SCHEMBL8324278 | 0.76 | CYP19A1 (0.51) | ALDH1A1MAPTNPSR1CYP1A2CYP2C9 | |
| SCHEMBL8879947 | 0.75 | ALDH1A1 (0.48) | ALDH1A1RECQLMAPTHPGDNPSR1 | |
| SCHEMBL8327014 | 0.75 | ALDH1A1 (0.46) | ALDH1A1RECQLMAPTHPGDTDP1 | |
| SCHEMBL695838 | 0.74 | ALDH1A1 (0.47) | ALDH1A1RECQLMAPTHPGDNPSR1 | |
| SCHEMBL8671264 | 0.74 | MAPT (0.58) | ALDH1A1RECQLMAPTHPGDTDP1 | |
| SCHEMBL8669276 | 0.74 | MAPT (0.53) | ALDH1A1RECQLMAPTHPGDTDP1 | |
| SCHEMBL8878531 | 0.72 | KMT2A (0.47) | ALDH1A1MAPTHPGDTDP1NPSR1 | |
| SCHEMBL10457648 | 0.72 | ALDH1A1 (0.56) | ALDH1A1MAPTHPGDNPSR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0729470-B1 | HERBICIDAL PYRROLOPYRIDINE COMPOUNDS | ZENECA LTD (GB) | 1999-05-12 | — | — | EP | disclosed |
| US-5451566-A | PREEMERGENCE AND POSTEMERGENCE HERBICIDES | ZENECA LIMITED (GB) | 1995-09-19 | — | — | US | disclosed |
| WO-1995014019-A1 | HERBICIDAL PYRROLOPYRIDINE COMPOUNDS | ZENECA LIMITED (GB) | 1995-05-26 | — | — | WO | disclosed |