Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.44 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8319911 | 0.84 | ALDH1A1 (0.48) | RECQLALDH1A1MAPTHPGDTDP1 | |
| SCHEMBL8323244 | 0.83 | RECQL (0.36) | RECQLALDH1A1MAPTHPGDTDP1 | |
| SCHEMBL8320585 | 0.81 | CDC7 (0.39) | RECQLALDH1A1MAPTHPGDTDP1 | |
| SCHEMBL8666821 | 0.80 | RECQL (0.54) | RECQLALDH1A1MAPTHPGDTDP1 | |
| SCHEMBL8327014 | 0.78 | ALDH1A1 (0.46) | RECQLALDH1A1MAPTHPGDTDP1 | |
| SCHEMBL8669276 | 0.77 | MAPT (0.53) | RECQLALDH1A1MAPTHPGDTDP1 | |
| SCHEMBL8671264 | 0.77 | MAPT (0.58) | RECQLALDH1A1MAPTHPGDTDP1 | |
| SCHEMBL8324278 | 0.77 | CYP19A1 (0.51) | ALDH1A1MAPTNPSR1CYP1A2CYP2C9 | |
| SCHEMBL8879947 | 0.73 | ALDH1A1 (0.48) | RECQLALDH1A1MAPTHPGDNPSR1 | |
| SCHEMBL8666096 | 0.73 | MAPT (0.55) | RECQLALDH1A1MAPTHPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0729470-B1 | HERBICIDAL PYRROLOPYRIDINE COMPOUNDS | ZENECA LTD (GB) | 1999-05-12 | — | — | EP | disclosed |
| US-5451566-A | PREEMERGENCE AND POSTEMERGENCE HERBICIDES | ZENECA LIMITED (GB) | 1995-09-19 | — | — | US | disclosed |
| WO-1995014019-A1 | HERBICIDAL PYRROLOPYRIDINE COMPOUNDS | ZENECA LIMITED (GB) | 1995-05-26 | — | — | WO | disclosed |