Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | HPGD | P15428 | 5/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | NPY1R | P25929 | 1/20 | 0.46 |
| ▸ | NPY2R | P49146 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8666821 | 0.82 | RECQL (0.54) | MAPTALDH1A1HPGDTDP1NPSR1 | |
| SCHEMBL8671731 | 0.82 | MAPT (0.53) | MAPTALDH1A1HPGDTDP1NPSR1 | |
| SCHEMBL8671264 | 0.80 | MAPT (0.58) | MAPTALDH1A1HPGDTDP1NPSR1 | |
| SCHEMBL8879948 | 0.78 | FFAR4 (0.42) | MAPTALDH1A1HPGDTDP1NPSR1 | |
| SCHEMBL8666096 | 0.78 | MAPT (0.55) | MAPTALDH1A1HPGDTDP1NPSR1 | |
| SCHEMBL8324428 | 0.77 | RECQL (0.51) | MAPTALDH1A1HPGDTDP1NPSR1 | |
| SCHEMBL8878531 | 0.76 | KMT2A (0.47) | MAPTALDH1A1HPGDTDP1NPSR1 | |
| SCHEMBL19089678 | 0.75 | RPS6KA5 (0.59) | MAPTALDH1A1HPGDHTTKDM4E | |
| SCHEMBL8319911 | 0.74 | ALDH1A1 (0.48) | MAPTALDH1A1HPGDTDP1NPSR1 | |
| SCHEMBL8327014 | 0.74 | ALDH1A1 (0.46) | MAPTALDH1A1HPGDTDP1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739353-A | N-arylindoles and their use as herbicides | ZENECA LIMITED (GB) | 1998-04-14 | — | — | US | disclosed |
| US-5599774-A | PRE- AND POSTEMERGENCE HERBICIDES FOR CROPS, PARTICULARLY CORN, RICE AND SOYBEANS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1997-02-04 | — | — | US | disclosed |
| US-5395817-A | N-pyridine substituted indoles | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1995-03-07 | — | — | US | disclosed |
| EP-0626946-A1 | N-PHENYLINDOLE AND N-PYRIDYLINDOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS HERBICIDES | ZENECA LIMITED (GB) | 1994-12-07 | — | — | EP | disclosed |
| WO-1993015049-A1 | N-PHENYLINDOLE AND N-PYRIDYLINDOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS HERBICIDES | ZENECA LIMITED (GB) | 1993-08-05 | — | — | WO | disclosed |