Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 9/20 | 0.60 |
| ▸ | RAB9A | P51151 | 7/20 | 0.60 |
| ▸ | NPC1 | O15118 | 6/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.60 |
| ▸ | TP53 | P04637 | 3/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | PDE4A | P27815 | 1/20 | 0.57 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.57 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.57 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | STAT1 | P42224 | 1/20 | 0.56 |
| ▸ | NQO1 | P15559 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14217138 | 0.91 | NPC1 (0.59) | KMT2AMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL13985921 | 0.86 | ALDH1A1 (0.58) | KMT2AMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL4818103 | 0.85 | PDE4A (0.72) | KMT2AMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL4818093 | 0.85 | PDE4A (0.72) | KMT2AMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7251263 | 0.85 | PDE4A (0.72) | KMT2AMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7251260 | 0.85 | PDE4A (0.72) | KMT2AMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL5072119 | 0.84 | KMT2A (0.69) | KMT2AMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL13985925 | 0.84 | RAB9A (0.59) | KMT2AMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL8322445 | 0.82 | PDE4A (0.79) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL8269855 | 0.80 | CTNNB1 (0.68) | KMT2AMAPTRAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004078144-A2 | DIPHENYLETHYLENE COMPOUNDS AND USES THEREOF | CELGENE CORPORATION (US) | 2004-09-16 | — | — | WO | disclosed |