Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23757992 | 0.79 | HSP90AA1 (0.48) | HSP90AA1ALDH1A1MAPTESR1ESR2 | |
| SCHEMBL8317686 | 0.76 | HSP90AA1 (0.46) | HSP90AA1ALDH1A1MAPTESR1ESR2 | |
| SCHEMBL19033787 | 0.74 | HSP90AA1 (0.63) | HSP90AA1ALDH1A1MAPTCA2CA4 | |
| SCHEMBL977997 | 0.74 | HSP90AA1 (0.63) | HSP90AA1ALDH1A1MAPTCA2CA4 | |
| SCHEMBL8322990 | 0.71 | HSP90AA1 (0.42) | HSP90AA1ALDH1A1MAPTESR1ESR2 | |
| SCHEMBL8320896 | 0.71 | HSP90AA1 (0.42) | HSP90AA1ALDH1A1ESR1ESR2CA2 | |
| SCHEMBL814 | 0.70 | HSP90AA1 (0.59) | HSP90AA1ALDH1A1MAPTESR1CA2 | |
| SCHEMBL7522374 | 0.70 | HSP90AA1 (0.59) | HSP90AA1ALDH1A1MAPTESR1CA2 | |
| SCHEMBL9642980 | 0.69 | ALDH1A1 (0.42) | HSP90AA1ALDH1A1MAPTCA2CA4 | |
| SCHEMBL4467471 | 0.67 | AKT1 (0.52) | HSP90AA1ALDH1A1MAPTHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856558-A | REACTING 2-FORMYL- OR 2-OXOALKYLIDENETRIPHENYLPHOSPHORANE WITH A CHLORINATING AGENT; HEATING; THEN NUCLEOPHILIC AGENT | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-01-05 | — | — | US | disclosed |
| US-5808129-A | Process for the preparation of novel stabilized phosphorus ylides | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-09-15 | — | — | US | disclosed |
| EP-0741138-A2 | Process for the preparation of novel stabilised phosphorus ylides | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-11-06 | — | — | EP | disclosed |