Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | TOP2A | P11388 | 8/20 | 0.39 |
| ▸ | TOP2B | Q02880 | 8/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9655734 | 0.90 | LMNA (0.52) | LMNAKDM4ESMN1; SMN2CYP1A2TOP2A | |
| SCHEMBL9033931 | 0.89 | LMNA (0.43) | LMNAKDM4ESMN1; SMN2CYP1A2TOP2A | |
| SCHEMBL8083425 | 0.85 | LMNA (0.70) | LMNAKDM4ESMN1; SMN2CYP1A2TOP2A | |
| SCHEMBL4638291 | 0.84 | LMNA (0.78) | LMNAKDM4ESMN1; SMN2CYP1A2ALDH1A1 | |
| SCHEMBL3890878 | 0.84 | LMNA (0.78) | LMNAKDM4ESMN1; SMN2CYP1A2ALDH1A1 | |
| SCHEMBL8202076 | 0.82 | LMNA (0.38) | LMNAKDM4ESMN1; SMN2CYP1A2TOP2A | |
| SCHEMBL9526680 | 0.81 | KDM4E (0.73) | LMNAKDM4ESMN1; SMN2CYP1A2TOP2A | |
| SCHEMBL8038099 | 0.80 | LMNA (0.53) | LMNAKDM4ESMN1; SMN2CYP1A2TOP2A | |
| SCHEMBL4393771 | 0.79 | KDM4E (0.55) | KDM4ESMN1; SMN2CYP1A2TOP2ATOP2B | |
| SCHEMBL6240622 | 0.79 | KDM4E (0.55) | KDM4ESMN1; SMN2CYP1A2TOP2ATOP2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705828-B1 | Quinolone- and naphthyridone carboxylic acid derivatives as antibacterial agents | BAYER AG (DE) | 1999-12-01 | — | — | EP | disclosed |
| EP-0705828-A1 | Quinolone- and naphthyridone carboxylic acid derivatives as antibacterial agents | BAYER AG (DE) | 1996-04-10 | — | — | EP | disclosed |