Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TOP2A | P11388 | 6/20 | 0.35 |
| ▸ | TOP2B | Q02880 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | ALB | P02768 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.35 |
| ▸ | TUBB | P07437 | 1/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.35 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.35 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.35 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8204201 | 0.87 | CNR1 (0.36) | LMNAKDM4EKMT2ATOP2ATOP2B | |
| SCHEMBL8206695 | 0.86 | STAT3 (0.38) | LMNAKDM4EKMT2ATOP2ATOP2B | |
| SCHEMBL10432848 | 0.85 | LMNA (0.51) | LMNAKDM4EKMT2ATOP2ATOP2B | |
| SCHEMBL9033931 | 0.84 | LMNA (0.43) | LMNAKDM4EKMT2ATOP2ATOP2B | |
| SCHEMBL8206595 | 0.84 | KDM4E (0.51) | LMNAKDM4ETOP2AALDH1A1HPGD | |
| SCHEMBL8913187 | 0.83 | CNR1 (0.31) | CNR1CNR2 | |
| SCHEMBL8320158 | 0.82 | LMNA (0.53) | LMNAKDM4EKMT2ATOP2ATOP2B | |
| SCHEMBL8202206 | 0.82 | KDM4E (0.30) | LMNAKDM4ESMN1; SMN2CYP1A2 | |
| SCHEMBL8911920 | 0.80 | LMNA (0.33) | LMNAKDM4EKMT2ATOP2ATOP2B | |
| SCHEMBL10433195 | 0.80 | STAT3 (0.50) | LMNAKDM4EKMT2ATOP2ATOP2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0770083-B1 | PYRIDO[3,2,1-i,j][3,1]BENZOXAZINE DERIVATIVES | BAYER AG (DE) | 2000-08-30 | — | — | EP | disclosed |
| EP-0770083-A1 | PYRIDO[3,2,1-i,j][3,1]BENZOXAZINE DERIVATIVES | BAYER AG (DE) | 1997-05-02 | — | — | EP | disclosed |
| WO-1996001829-A1 | PYRIDO[3,2,1-i,j][3,1]BENZOXAZINE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-01-25 | — | — | WO | disclosed |