Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | TOP2A | P11388 | 7/20 | 0.40 |
| ▸ | TOP2B | Q02880 | 7/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | ALB | P02768 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8320158 | 0.89 | LMNA (0.53) | LMNAKDM4ESMN1; SMN2CYP1A2TOP2A | |
| SCHEMBL8091043 | 0.84 | LMNA (0.58) | LMNAKDM4ESMN1; SMN2CYP1A2TOP2A | |
| SCHEMBL9582818 | 0.84 | LMNA (0.58) | LMNAKDM4ESMN1; SMN2CYP1A2TOP2A | |
| SCHEMBL9582803 | 0.84 | LMNA (0.58) | LMNAKDM4ESMN1; SMN2CYP1A2TOP2A | |
| SCHEMBL8202076 | 0.84 | LMNA (0.38) | LMNAKDM4ESMN1; SMN2CYP1A2TOP2A | |
| SCHEMBL9036043 | 0.83 | LMNA (0.46) | LMNAKDM4ESMN1; SMN2CYP1A2TOP2A | |
| SCHEMBL9034917 | 0.83 | KDM4E (0.55) | LMNAKDM4ETOP2AALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL9036371 | 0.82 | KDM4E (0.54) | LMNAKDM4ETOP2AALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL9035308 | 0.82 | LMNA (0.46) | LMNAKDM4ETOP2ATOP2BKMT2A | |
| Hydrochloric Acid SCHEMBL9035741 | 0.82 | LMNA (0.45) | LMNAKDM4ESMN1; SMN2TOP2ATOP2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0390135-B1 | Pyrroloquinoline derivatives, antimicrobial agents using the same and process for preparing the same | OTSUKA PHARMA CO LTD (JP) | 1996-06-05 | — | — | EP | claimed |