Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.56 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.55 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.55 |
| ▸ | MRGPRX4 | Q96LA9 | 6/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | CD74 | P04233 | 1/20 | 0.46 |
| ▸ | MIF | P14174 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4741778 | 0.86 | CYP4F2 (0.59) | LOXL2CYP4F2CYP4A11MRGPRX4TSHR | |
| SCHEMBL5341608 | 0.86 | MRGPRX4 (0.52) | MRGPRX4RAB9ASMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL31245947 | 0.85 | CA12 (0.44) | LOXL2CYP4F2CYP4A11KDM4EALDH1A1 | |
| SCHEMBL23090473 | 0.85 | CA1 (0.44) | LOXL2CYP4F2CYP4A11MRGPRX4TSHR | |
| SCHEMBL21068861 | 0.84 | CYP4F2 (0.60) | LOXL2CYP4F2CYP4A11MRGPRX4TSHR | |
| SCHEMBL5449158 | 0.84 | PTPN11 (0.44) | LOXL2CYP4A11MRGPRX4RAB9ASMN1; SMN2 | |
| SCHEMBL12095859 | 0.83 | SMN1; SMN2 (0.41) | MRGPRX4TSHRRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL28001418 | 0.83 | RAB9A (0.42) | LOXL2CYP4F2CYP4A11MRGPRX4TSHR | |
| SCHEMBL31371244 | 0.83 | MRGPRX4 (0.53) | MRGPRX4RAB9ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL31385466 | 0.83 | MRGPRX4 (0.53) | MRGPRX4RAB9ASMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6001561-A | AN ANALYTE-SPECIFIC BINDING MEMBER CONJUGATED TO A CHEMILUMINESCENT COMPOUND; FOR SENSITIVE AND ACCURATE ANALYSIS AND FOR CONTROLLING TIMING OF LUMINESCENT REACTION | ABBOTT LABORATORIES (US) | 1999-12-14 | — | — | US | disclosed |